Why Get Shingles Herpes And Other Herpes Viruses

The Herpesviridae are a large family of herpes viruses that cause disease in humans and animals. The word derives from the Greek word “herpein,” which means “to creep.” The disease shingles, genital herpes or cold sores are all similar in that they remain within the body, dormant at times, and recur later on. The symptoms of shingles herpes sometimes mimic other types of herpes with blistering, itching and pain. Additionally, there is no proven “cure” for this classification of virus yet, although there are ways to limit risk and treat symptoms.

For microbiologists, the most telltale sign of herpes viruses, including shingles, is large double-stranded, linear DNA genomes that encode 100 to 200 genes containing viral proteins and viral mRNAs, which enable it to replicate quickly within the cells. What triggers the Herpesviridae and what causes shingles exactly is still unknown. At the start of the infection, the herpes virus particle looks for certain types of vulnerable receptor molecules on cell surfaces. Once the viral envelope glycoproteins bind to the cell membrane’s receptors, the virion gets inside the cell nucleus, where viral DNA replication begins. After the primary infection subsides, the latent virus remains in the body for years. Later, they may be reactivated to cause a headache, fever, painful rash, swollen lymph nodes and a depleted level of “killer” T-cells.

Herpes viruses have certain symptomatic traits in common as well. For instance, the chickenpox virus, shingles herpes virus and the herpes simplex virus (known as oral or genital herpes) target the mucoepithelial cells, which is what causes the pain-riddled rash and blistering common to both varieties. Similar feelings of intense itching, burning and pain accompany these maladies. Once the initial outbreak has subsided, the Herpesviridae family generally remains latent in the body, causing no symptoms for years before reappearing again. The shingles symptoms and herpes symptoms almost always occur during periods of heightened stress or weakened immune system function.

There is no 100% proven cure for the herpes family yet, but the medication treatment available is often helpful in alleviating some of the suffering and lessening the outbreaks’ duration or severity. For example, the herpes zoster vaccine is recommended for people who are 60+ to significantly reduce their risk of a shingles herpes outbreak, and people who already show signs of shingles can receive antiviral medication within 72 hours to prevent serious complications from the virus, as well as pain medication to treat that aspect of it. Similarly, there are many products on the market targeting cold sore herpes, such as Denavir, Zovirax, Famvir and Valtrex.

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